Mostly play the tame ones, bc of story focus. The most intense I'm planning on reading would be Fraternite, as I friend told me it would be an even more insane version of Euphoria with only bad endings if I recall him correctly.
As for the ones I've read: I think Sharin no Kuni was pretty intense on a realization level. Was less grotesque with h-content, but more on the social/psychological side imo.